By Carsten H. Meyer
Chromovitrectomy is a singular method of visualize the vitreous or retinal floor in the course of vitreoretinal surgical procedure. in recent times, the generally used indocyanine eco-friendly (ICG) has made the surgical maneuver of internal proscribing membrane peeling greatly more secure and effective. additionally, a variety of dyes were utilized in experimental settings with promising or devastating effects. This quantity highlights the main medical and experimental result of presently used novel very important dyes. the 1st chapters describe the obvious constitution of the vitreous physique and summarize historic issues to imagine its constitution by way of optical coherence tomography, dye injections or autologous cells in the course of surgical procedure and for diagnostic purposes.The following contributions describe the benefits and downsides of ICG in the course of vitreoretinal surgical procedure and experimental functions. substitute techniques by means of lately authorized very important dyes reminiscent of trypan blue, patent blue and exceptional blue are evaluated within the next chapters. ultimately the previous couple of chapters supply an outlook on novel very important dyes, that are at the moment lower than overview, in addition to substitute enzymatic techniques to take away the vitreous from the retinal floor. Being a well timed replace this booklet might be vital examining for vitreoretinal surgeons and ophthalmic researchers.
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Extra info for Vital Dyes in Vitreoretinal Surgery: Chromovitrectomy (Developments in Ophthalmology, Vol. 42)
Example text
Eyes with a significant breakdown of the blood-retinal barrier accumulate intravenously applied vital dyes, for example fluorescein, in the vitreous cavity. 05 ml autologous blood may help to stain transparent vitreous structures and visualize the remaining vitreous. Intravitreous triamcinolone crystals attach to the surface of the vitreous cortex, bursa premacularis or retina itself allowing better visualization of a controlled vitreous removal. A preoperative diagnostic fluorescein angiography in eyes with active uveitis or diabetic retinopathy may lead to a moderate accumulation of the dye in the vitreous cavity and greenish staining of the vitreous cortex at the vitreoretinal interface.
Anomalous PVD may be the inciting event in each of these conditions [58]. However, as mentioned above, the topographic and structural features that were detected in eyes with macular holes and eccentric retinal contraction differed in comparison to eyes with macular pucker alone [57], suggesting that while each condition may begin 20 Sebag Fig. 12. Three-dimensional OCT-SLO Imaging of vitreopapillary traction. The color OCT image can be intersected with the grayscale SLO fundus image to detect exactly where on the fundus an OCT finding is located.
006). 0001). High-resolution time domain OCT-SLO and the newer spectral domain imaging technologies have provided even more powerful methods with which to evaluate the vitreoretinal interface. As a result, new concepts of disease pathogenesis are evolving. For example, vitreoschisis, defined as a split in the posterior vitreous cortex, has pre- To See the Invisible: The Quest of Imaging Vitreous 19 a b c d Fig. 11. Coronal plane imaging of macular pucker with combined OCT-SLO. Superimposing coronal plane OCT color images upon the SLO grayscale fundus image reveals multifocality (arrows) in the topography of macular pucker.