Download Oxygen Transport to Tissue XXXIII by Duane F. Bruley (auth.), Martin Wolf, Hans Ulrich Bucher, PDF

By Duane F. Bruley (auth.), Martin Wolf, Hans Ulrich Bucher, Markus Rudin, Sabine Van Huffel, Ursula Wolf, Duane F. Bruley, David K Harrison (eds.)

Based at the thirty eighth annual convention of the foreign Society on Oxygen shipping to Tissue (ISOTT), held in Ascona, Switzerland in July 2010, this quantity covers all elements of oxygen delivery from air to the cells, organs and organisms; instrumentation and techniques to feel oxygen and scientific evidence.

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Nonpulsatile CPB results in cerebral capillary collapse, intravascular sludging, and vasodilation [6] and may lead to arteriovenous shunting. Therefore, arteriovenous shunting might induce a high SjvO2 associated with inadequate tissue oxygenation and cognitive decline. Although a higher SjvO2 was observed, T-SO2 measured using TRS did not show a high value in the decline group. One possible reason is that differences may exist between global and regional cerebral oxygenation. If so, the monitoring of both SjvO2 and T-SO2 may be useful not only for detecting the occurrence of cognitive decline, but also for clarifying the mechanisms of neuropsychological dysfunction after cardiac surgery.

BS blood sugar, Hb hemoglobin concentration, Ca-jvO2 arteriojugular venous oxygen content, COER cerebral oxygen extraction ratio 22 Y. Kakihana et al. 3 Postoperative Cognitive Dysfunction and Cerebral Monitoring by Time-Resolved NIRS 23 Fig. 1 Changes in SjvO2 and T-SO2 during CPB between the normal and decline groups. Significant differences between the SjvO2 and T-SO2 values were observed in the decline group but not in the normal group. SjvO2 jugular venous oxygen saturation; T-SO2 regional cerebral oxygenation Fig.

Arterial oxygen content depends on the concentration of hemoglobin and the blood oxygen tension, oxygen delivery on the content and the blood flow. There have been measurements and estimates of the spatial distribution of oxygen tensions in the parenchyma. C. edu M. Wolf et al. C. LaManna the venous pO2. Finally, the oxygen distribution is not constant with time, but varies with neuronal activity. When the neurons are activated, the blood flow and oxygen delivery to that locality are increased, so that transient capillary arterialization occurs and can be measured by the blood oxygen level dependent (BOLD) technique of functional magnetic resonance imaging (fMRI) [3].

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