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By John T. Landrum, John Nolan

''This publication outlines the pathological stipulations of the important retina the place the macular pigment is understood to have its maximum involvement in safety opposed to photooxidative harm. The e-book specializes in the character of the macular carotenoids, their delivery and accumulation in the retina, and their impression at the etiology of retinal illnesses. it's also chapters that supply readers an figuring out of Read more...

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Carotenoids and retinal disease

''This publication outlines the pathological stipulations of the relevant retina the place the macular pigment is understood to have its maximum involvement in safety opposed to photooxidative harm. The publication specializes in the character of the macular carotenoids, their delivery and accumulation in the retina, and their impression at the etiology of retinal ailments.

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H. Koh, et al. (2000a). ” Ophthalmic Physiol Opt 20(2): 105–111. , H. H. Koh, et al. (2000b). ” Surv Ophthalmol 45: 115–134. , J. Nolan, et al. (2004). ” Arch Biochem Biophys 430(1): 70–76. Berendschot, T. T. and D. van Norren. (2004). ” Arch Biochem Biophys 430: 149–155. Berendschot, T. , P. J. DeLint, et al. (2003). ” Prog Retin Eye Res 22(2): 171–200. Bernstein, H. N. and J. Ginsberg (1964). ” Arch Ophthalmol 71: 238–245. , D. Zhao, et al. (2004). ” Arch Biochem Biophys 430: 163–169. , A. J.

Macular Pigment 11 It is plausible that oxolutein might be efficiently reduced by this pathway to form meso-zeaxanthin. Similar pathways are known in other animal species (Maoka et al. 1986). Traces of S,S-zeaxanthin have also been detected within the retina and its presence would be consistent with this hypothesized reductive pathway (Bone et al. 1993). The recent isolation by Bernstein et al. (see Chapter 9) of two distinct human xanthophyll-binding proteins, GSTP 1 and the StAR D3, which specifically bind lutein and zeaxanthin, move us a step closer to answering the mechanism involved in the accumulation of L and Z within the retina (Bhosale et al.

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