Download The Vitreous: Structure, Function, and Pathobiology by J. Sebag PDF

By J. Sebag

The vitreous physique lengthy has been the main mysterious of all ocular constructions, owing probably to its seeming simplicity. there were few concerted, sustained efforts to resolve the mysteries of the way the vitreous consists and what position it performs in general body structure. through the years, although, many experiences have produced self reliant findings relating vitreous biochemistry, constitution, and body structure. The Vitreous organizes those findings right into a well-constructed compendium that not just addresses the most up-tp-date clinical wisdom, but additionally studies ancient perspec­ tives in a fashion that lends richness to the scope of the publication. the 1st few chapters current an exhaustive, but readable, evaluation of the physique of medical facts that experience come from laboratories and researchers through the international. broad bibliographies direct readers additional into particular features of the elemental technological know-how of the vitreous. bankruptcy II: "Embryology" and bankruptcy IV: "Structure" current a singular organizational method of assembling and providing information in an built-in demeanour. bankruptcy V: "Functions" and bankruptcy VI: "Development and getting older" introduce clean views at the value of the vitreous as a few­ other thing than a vestigial house filler in the eye.

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Extra resources for The Vitreous: Structure, Function, and Pathobiology

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9% wt/wt of the total residual fraction. Kim and Cotlier (1976) demonstrated that the major fatty acid in the rabbit vitreous is palmitic acid. In their studies the distribution of phospholipids 27 in the vitreous was similar to that in the lens and aqueous. In all these tissues, phospholipid concentrations were lower than serum levels. These investigators concluded that there exists a bloodvitreous barrier restricting phospholipid transport into the eye. Reddy et al (1986) found evidence to suggest active lipid metabolism in the vitreous of dogs and humans.

The vitreous base also contains intact cells that are fibroblast-like anterior to the ora serrata, and macrophage-like posteriorly (Gartner, 1971). Damaged cells in different stages of involution and fragments of basal laminae, presumed to be remnants of the embryonic hyaloid vascular system, are also present in the vitreous base. (Gartner, 1971; Chapters II-A2 and VII-D3a). D. Vitreous Cortex The vitreous cortex is defined as the peripheral "shell" of the vitreous that courses forward from the anterior vitreous base to form the anterior vitreous cortex, and posteriorly from the posterior border of the vitreous base to form the posterior vitreous cortex.

Am ] Vet Res 48:467;473. Meyer K (1958): Chemical structure of hyaluronic acid. Fed Proc 17: 1075-1077. Meyer K, Palmer JW (1934): The polysaccharide of the vitreous humor. ] BioI Chem 107:629-634. Meyer FA, Koblenz M, Silberberg A (1977): Structural investigation of dextran fractions as non-interesting macromolecular probes. BiochemJ 161:285-29l. Oegema TR Jr, Brown M, Dziewiatkowski DD (1977): The link protein in proteoglycan aggregates from the Swarm rat chondrosarcoma. ] BioI Chem 252:6470-6477.

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