By Roger G.Gosden Phd DSc, Togas Tulandi, Roger Gordon Gosden
Many applied sciences exist for women and men to maintain fertility, and advances are being made for all time. unfortunately, this knowledge isn't really continuously popular within the oncology group and is, hence, no longer provided to all eligible melanoma sufferers. Reflecting the newest advances within the box and providing useful details valuable to clinicians and scientists, protection of Fertility addresses new ideas, development in reproductive concepts, novel therapy modalities, being pregnant after melanoma therapy, sufferer care concerns, duties.
Tulandi and Gosden have assembled an excellent staff of the world over well-known experts to deal with the complete spectrum of matters relating to fertility maintenance. they start with a dialogue of age and fertility, epidemiology of melanoma survival and fertility, and the vulnerability of the reproductive approach to radiotherapy and chemotherapy. The ebook contains insurance of tools for retaining fertility, new advancements within the laboratory for protecting gametes and gonadal tissue, and the psychosocial, criminal, and moral problems with fertility renovation. a strong wisdom software for the clinical group, this pioneering booklet presents a whole figuring out of the strategies for maintaining fertility
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Extra resources for Preservation of fertility
Sample text
In conclusion, IUGR does not appear to significantly influence fetal ovarian development in humans. However, data from the 1944 Dutch famine indicate that severe malnutrition, experienced in early childhood, can advance age at menopause by almost 2 years . 89 90 36 Figure 7 T h e a g e variations of the main reproductive events in w o m e n probably show parallel distributions. Reproduced with permission from reference 1 exert their influence on the development of the follicle pool during fetal life, or affect follicle decline by atresia postnatally.
In te Velde ER, Pearson PL, Broekmans FJ, eds. Female Reproductive Aging. Carnforth, UK: Parthenon Publishing Group, 2 0 0 0 : 1 3 7 ^ 8 van Asselt KM, Kok HS, Putter H, et al. Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative trait loci influencing variation in human menopausal age. In van Asselt KM, Kok HS. Age at Menopause; A Genetic-Epidemiologic Study. Utrecht: University Utrecht, 2 0 0 3 Klein NA, Battaglia DE, Fujimoto VY, et al. Reproductive aging: accelerated ovarian follicular d e v e l o p m e n t associated with a monotrophic follicle-stimulating h o r m o n e rise in normal older women.
Van Blerkom J, Antczak M, Schräder R. T h e developmental potential of the human oocyte is related to the dissolved oxygen content of follicular fluid: association with vascular endothelial growth factor levels and perifollicular blood flow characteristics. Hum Reprod 1997;12:1047-55 54. Manau D, Balasch J, J i m e n e z W, et al. Follicular fluid concentrations of adrenomedullin, vascular endothelial growth factor and nitric oxide in IVF cycles: relationship to ovarian response. Hum Reprod 2 0 0 0 ; 15: 1295-9 55.