By M. R. El-Gewely
Development within the functions of biotechnology is determined by a large base of easy in addition to technologies. The output of biotechnology has already proved itself in lots of diversified fields, from health and wellbeing to biomining, and from agriculture to enzyme ''breeding''.
The targets of the Biotechnology Annual Review sequence is to supply readers with the wanted in-depth wisdom through reviewing particular themes in each one quantity. during this manner, it truly is more straightforward for scientists to maintain involved with development and purposes in biotechnology.
Up-to-date themes are reviewed which are concerning regulatory affairs, social effect, biodiversity and patent matters, in addition to creation and technology.
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Proc Natl Acad Sci USA 1995;92:679-683. 56. Midkkelsen TR, Brandt J, Larsen HJ, Larsen BB, Poulsen K, Ingerslev J, Din N, Hjorth JF? Tissue-specific expression in the salivary glands of transgenic mice. Nucl Acids Res 1992;20: 2249-2255. 57. Rancourt DE, Peters ID, Walker VK, Davies PL. Wolfish antifreeze protein from transgenic Drosophila. BiolTechnology 1990;8:453-457. 58. Peters ID, Rancourt DE, Davies PL, Walker VK. Isolation and characterization of an antifreeze protein precursor from transgenic Drosophila: evidence for partial processing.
Larger genes as for FVIII and entire genetic loci, such as those of immunoglobulins or hemoglobin, may be expressed using the yeast artificial chromosome technology [106], P1 cloning systems [ 1351 or by the extrachromosomal homologous recombination of overlapping DNA fragments [ 1051. The unlimited availability of safer, cheaper blood proteins will lead to the increased use of FVIII and FIX in prophylaxis, and allow the storage of large amounts of rHb products for emergency use at times of blood shortage.
Bio/Technology 1991;9:844-847. 41. Krimpenfort P. The production of human lactoferrin in the milk of transgenic animals. Cancer Detect Prev 1993;17:301-305. 42. Gordon KI, Lee E,Vitale JA, Smith AE,Westphal H, Hennighausen L. Production of human tissue plasminogen activator in transgenic mouse milk. Bio/Technology 1987;5:1183- 1187. 43. Purse1 VG, Pinkert CA, Miller KF, Bolt DJ, Campbell RG, Palmiter RD, Brinster RL, Hammer RE. Genetic engineering of livestock. Science 1989;244:1281- 1287. 44. Hennighausen L.