Download Biofabrication. Micro- and Nano-fabrication, Printing, by Gabor Forgacs, Wei Sun PDF

By Gabor Forgacs, Wei Sun

Biofabrication is a realistic advisor to the radical, inherently cross-disciplinary clinical box that specializes in biomanufacturing tactics and a comparable variety of rising applied sciences. those tactics and applied sciences eventually additional the advance of goods that can contain residing (cells and/or tissues) and nonliving (bio-supportive proteins, scaffolds) parts. The publication introduces readers to mobilephone printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips as a coherent micro-/nano-fabrication toolkit. Real-world examples illustrate easy methods to follow biofabrication concepts in parts similar to regenerative drugs, prescription drugs and tissue engineering.

In addition to being an essential reference for scientists, engineers and technicians trying to observe biofabrication concepts, this publication additionally presents an perception into destiny advancements within the box, and capability new functions.

  • Discover the multi-disciplinary toolkit supplied via biofabrication and use it on boost new items, options and therapies
  • Covers a variety of vital rising applied sciences in a coherent demeanour: phone printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips...
  • Readers advance the facility to use biofabrication applied sciences via useful examples

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Additional resources for Biofabrication. Micro- and Nano-fabrication, Printing, Patterning and Assemblies

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Upper insert) Microscopic view of cross-sectional ring showing rhythmic contractions at day 9; (lower insert) Masson’s trichrome staining of ring thin section harvested for force generation studies after 10 d in vitro (scale bar, 50 m). (Bottom) Force generation in nonperfused rings at day 10, after 1-Hz (left) or 2-Hz (right) electrical stimulation. (d) (Left) Representative functional assessment tracing of decellularized whole heart construct paced in a working heart bioreactor preparation at day 0.

49] Badylak SF, Freytes DO, Gilbert TW. Extracellular matrix as a biological scaffold material: structure and function. Acta Biomater 2009;5:1À13. [50] Badylak SF, Taylor D, Uygun K. Whole-organ tissue engineering: decellularization and recellularization of three-dimensional matrix scaffolds. Annu Rev Biomed Eng 2011;13:27À53. [51] Yoo JJ, Meng J, Oberpenning F, Atala A. Bladder augmentation using allogenic bladder submucosa seeded with cells. Urology 1998;51:221À5. [52] Dahl SL, Koh J, Prabhakar V, Niklason LE.

Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems. Trends Biotech 2004;22:354À62. [35] Hollister SJ. Porous scaffold design for tissue engineering. Nat Mater 2005;4:518À24. [36] Lee JW, Lan PX, Kim B, Lim G, Cho DW. Fabrication and characteristic analysis of a poly (propylene fumarate) scaffold using micro-stereolithography technology. J Biomed Mater Res B 2008;87:1À9. [37] Kang HW, Seol YJ, Cho DW. Development of an indirect solid freeform fabrication process based on microstereolithography for 3D porous scaffolds.

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